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November 20, 1948

Myotonia: Thomsen's Disease (Myotonia Congenita), Paramyotonia, and Dystrophia Myotonica: A Clinical and Heredobiologic Investigation

JAMA. 1948;138(12):931. doi:10.1001/jama.1948.02900120073040

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This excellent review and report of new cases of myotonia comes from the hospitals and scientific departments associated with the University of Copenhagen and from the Institute for Human Genetics in Denmark. The translation from Danish into English, although a little stilted, is so good that the author's meaning is seldom unclear. The various forms of myotonia are fully delineated, the text being supplemented by pertinent illustrations, an adequate bibliography and case reports of twenty families. The book only lacks an index to make it a completely useful monograph on two syndromes of muscular disability. To Thomsen's original concept of myotonia congenita, first described from his own symptoms in 1876, has been added a subvariety, paramyotonia. Dystrophia myotonica, which the author feels is a different disease, also has myotonia as one of its symptoms. Myotonia acquisita, a nonhereditary type of myotonia, does not, in Thomasen's opinion, have sufficient basis for

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