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November 27, 1948

The Clinical Picture of Thyrotoxicosis

JAMA. 1948;138(13):1004-1005. doi:10.1001/jama.1948.02900130068033

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This small volume represents the effort of a Yorkshire surgeon to portray the clinical picture of thyrotoxicosis from a "practical" point of view. It is highly personalized, and is based on the author's experience with about two thousand thyroidectomies over a period of twenty-five years. It contains twenty-five sections dealing with such aspects of thyrotoxicosis as the classical signs and symptoms, the cardiac state, the basal metabolic rate, ocular phenomena, thyrotoxicosis and pregnancy, the thyrotoxic crisis, differential diagnostic problems, and general considerations of surgical treatment and the use of thiouracil and related compounds. The twenty-fourth section is devoted to an attempt to analyze and interpret the mortality statistics for thyroid disease from the office of the Registrar-General for England and Wales from 1913 through 1945.

Unfortunately this effort possesses many faults and few virtues. The author's treatment of his subject is based almost entirely on personal impressions which are submitted

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