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January 1, 1949


Author Affiliations

San Francisco

JAMA. 1949;139(1):50. doi:10.1001/jama.1949.02900180052021

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To the Editor:—  Dr. Edmond Farris has published a number of articles on his rat test for determining the time of ovulation. His latest paper appeared in The Journal, Oct. 23, 1948. The essence of these reports is that by noting the degree of hyperemia of the immature rat ovary after injection of the patient's urine the day of ovulation (hereafter referred to as Farris's day of ovulation, or FDO) can be determined. To prove the accuracy of his method he presents data on patients who were inseminated by coitus or artificially on the FDO and who conceived during that same menstrual cycle. This clinical test of his method would be quite acceptable but for one omission. Dr. Farris does not state that the insemination depicted in his charts was the only insemination in the cycle, or that insemination occurred only in a single twenty-four hour period at the FDO.

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