The extreme variation which body weight may undergo is indeed remarkable. There is a report, probably true, of a man weighing over 1,000 pounds (453.5 Kg.), while a subject weighing 779 pounds (353.3 Kg.) has been studied by competent observers.1 At the other extreme, a 30 year old woman has recently been observed at the Mayo Clinic who weighed 44 pounds (20 Kg.) and was 5 feet 3.5 inches (161.3 cm.) in height.
While such spectacular deviations attract interest, lesser grades of underweight and overweight are of great importance in the health of the individual and are of much greater importance from the standpoint of public health than are sideshow freaks. In the latter half of life even moderate obesity is dangerous, and it has been shown that between the ages of 45 and 50 years 25 pounds (11.3 Kg.) of excess weight results in an increase of 25
GASTINEAU CF, RYNEARSON EH, IRMISCH AK. TREATMENT OF THE FAT AND THE LEAN. JAMA. 1949;139(2):86–91. doi:10.1001/jama.1949.02900190016005
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