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Article
January 22, 1949

THE CLINICAL USE OF FLUORESCEIN

JAMA. 1949;139(4):250. doi:10.1001/jama.1949.02900210056025

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Abstract

To the Editor:—  With reference to the recent article by Gerald J. Menaker and Morris L. Parker in the Dec. 4, 1948 number of The Journal, page 1039, it is pertinent to point out that many observers are finding a variety of uses for fluorescein in medicine.Since 1946, fluorescein has been incorporated into several different technics at the University of Minnesota Hospitals. The most valuable among these has been a method of locating subcortical brain lesions. This procedure has been described in detail in the July 1948 issue of The Journal of Neurosurgery.In addition to the use of the dye in the operating room, radioactive diiodofluorescein (I131) has been employed in the attempt to locate tumors of the central nervous system preoperatively. This procedure was described in Science (107: 569 [May 28] 1948) and in Minnesota Medicine (31:1073-1076 [Oct.] 1948).In an attempt to make brain

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