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Article
February 12, 1949

POSTPHLEBITIC SEQUELAE

JAMA. 1949;139(7):423-429. doi:10.1001/jama.1949.02900240001001
Abstract

Within the past decade many investigations have been made and much has been written concerning venous thrombosis, but relatively little attention has been paid to the sequelae of venous clotting. Without question the best treatment of the complications and sequelae of thrombophlebitis and phlebothrombosis is prophylaxis, i. e., the adequate and prompt therapy of the originating venous lesion. Unfortunately, however, some patients are not seen at the time of their original venous lesion and there are many in whom appropriate therapy is not instituted promptly enough. From our clinical and experimental investigations, we are convinced that it is necessary to differentiate between two types of venous thrombosis, which differ from each other as much as night from day.1 Although both have in common a clot within the vein, they are dissimilar from etiologic, pathologic, clinical, prognostic and therapeutic points of view, and, unless the clinician who is treating a

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