Extensive chemical research carried out in recent years has produced a rodenticide, sodium fluoroacetate, which has been found to be very effective and extremely toxic. Sodium fluoroacetate, or "1080" as it was called during the investigation period, is said to be one of the most noxious substances known, since it is toxic to all mammals, man included. Sodium fluoroacetate was first reported by Kalmbach. With this poison rat control can be much more easily and effectively carried out than ever before; however, because of its extreme toxicity (three teaspoons of the watered solution used for rats is sufficient to cause death in the adult human being) many necessary precautions have been taken in its employment and administration. It is distributed only to qualified members of governmental agencies and to properly insured and licensed pest control agencies and operators. In addition, strict regulations are imposed upon its use, and standard procedures
Brockmann JL, McDowell AV, Leeds WG. FATAL POISONING WITH SODIUM FLUOROACETATE: REPORT OF A CASE. JAMA. 1955;159(16):1529–1532. doi:10.1001/jama.1955.02960330029010
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