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January 7, 1956

SKELETAL LESIONS FOLLOWING INTERNALLY ADMINISTERED RADIUM

JAMA. 1956;160(1):41-44. doi:10.1001/jama.1956.02960360043009
Abstract

Many reports have appeared in the literature documenting cases of injury or death by internally deposited radioactive substances, but few cases illustrating the late effects of these substances in man were reported until 1952, when Aub, Evans, Hempelmann, and Martland reported a series of 30 such cases. The following report describes an additional case that would fall into their group 4 category, those with a body radium content of less than 0.7 meg. They had four patients in this group, all of whom are alive and one of whom exhibited bone changes similar to those in the case to be described.

REPORT OF A CASE

A 58-year-old man was first seen in 1948 with the complaint of incapacitating arthritis of many years' duration. History of the condition dated back to childhood, when he first noted the gradual onset of pain on walking associated with tenderness of the knees, ankles, and

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