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January 28, 1956

The Mechanisms of Healing in Human Wounds: A Correlation of the Clinical and Tissue Factors Involved in the Healing of Human Surgical Wounds, Burns, Ulcers, and Donor Sites

JAMA. 1956;160(4):338. doi:10.1001/jama.1956.02960390088032

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The author in his foreword says: "This description of the processes and factors involved in the healing of human wounds is offered to all physicians, surgeons and students. It is a practical concept of the healing processes which may be applied to a more complete understanding of human wounds and to the selection of proper techniques for the repair or treatment of wounds." This little monograph includes a short summary, an adequate bibliography, and an index. The author stresses the fact that too much attention has been given to the histological findings of wound healing in laboratory animals and too little to the histological findings in human wounds. He believes that the cellular findings regarding fibroplasia in human wounds, which heal by primary intention, give strong support to the concept that mononuclear cells, especially the lemmocytes, provide the substance found in the repair of all white, fibrous, connective tissue in

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