• Intestinal lipodystrophy is manifested in various gastrointestinal symptoms and in characteristic roentgen findings. The barium pattern in the small intestine is one of mucosal coarseness and flocculation or clumping with discontinuity of the column. In addition, certain extraintestinal manifestations aid in making the diagnosis. These are well illustrated in the four cases described.
In each instance, the intestinal manifestations were typical. The extraintestinal manifestations included enlargement of mediastinal, retroperitoneal, or peripheral lymph nodes; narrowing of the hip joints; and arthritic changes in the sacroiliac joints. A widening of the duodenal loop observed in one patient was ascribed to pressure from a mass of enlarged retroperitoneal lymph nodes.
Patients in whom the symptoms and intestinal roentgen findings suggest lipodystrophy should have further roentgen studies of the duodenal loop, the chest, and the sacroiliac joints.
Eyler WR, Doub HP. EXTRAINTESTINAL ROENTGEN MANIFESTATIONS OF INTESTINAL LIPODYSTROPHY. JAMA. 1956;160(7):534–536. doi:10.1001/jama.1956.02960420014003
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