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Article
February 25, 1956

CLINICAL NOTES

JAMA. 1956;160(8):656-662. doi:10.1001/jama.1956.02960430046009
Abstract

HUGE OMPHALOCELE RUPTURED IN UTERO 

SUCCESSFUL OUTCOME AFTER EXTENSIVE RESECTION OF INTESTINE  Adolph Meltzer, M.D., Worcester, Mass.Omphalocele, a form of aplasia of the abdominal wall, is not a rare anomaly in the newborn infant. The incidence is generally conceded to be about 1 in 5,000 births. Well over 500 cases have been reported since 1900, and the bibliography encompasses some 60 publications. According to Gross,1 "Prior to 1940, rupture of an omphalocele sac was a uniformly fatal accident... always followed by peritonitis. Since the advent of chemotherapy and antibiotics, this outlook has now completely changed." Current reports in the literature appear to share this optimism2 and indicate that the "antibiotic era" has gone far toward adding this serious anomaly to its increasing list of successes. The following case represents the only report in the literature in which intestinal resection was successfully performed in conjunction with the repair

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