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March 31, 1956

Subacute Bacterial Endocarditis

JAMA. 1956;160(13):1182. doi:10.1001/jama.1956.02960480082029

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This is a well-documented, scholarly presentation of present knowledge of subacute bacterial endocarditis. The author not only has reviewed 800 original articles that are listed as references but has delved into the archives to find references to this condition in the writings of Lancisi, Morgagni, Corvisart, and others. The important contributions of Horder and Libman are given proper credit. There is an excellent chapter on etiology followed by chapters on the clinical findings and treatment. The importance of early treatment, even when an absolute diagnosis by blood culture has not been made, is emphasized. The value of the different antibiotics is weighed in the light of results reported in the literature, and it is concluded that only the bactericidal antibiotics are of real value. Therefore, although the organism obtained from the blood culture may show a high degree of sensitivity to such bacteriostatic agents as the sulfonamides or tetracycline, treatment

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