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June 18, 1949

CHRONIC LYMPHATIC LEUKEMIAA Study of 100 Patients Treated with Radioactive Phosphorus

JAMA. 1949;140(7):585-588. doi:10.1001/jama.1949.02900420005002

In a previous article1 were reported 129 cases of chronic myelogenous leukemia treated primarily with radioactive phosphorus (P32). In the present paper a similar study of lymphatic leukemia is presented, based on our total experience in the use of P32 since we started these investigations. Included in the series of 100 cases are all patients with this condition who have been treated with radioactive phosphorus at the University of California in Berkeley and San Francisco since the work was started by one of us in 1936 until March 1, 1947, and followed until Sept. 1, 1948.

PREPARATION OF RADIOPHOSPHORUS  P32 in the form of isotonic sodium mono-hydrogen phosphate was prepared according to methods previously described.2 The former source of the P32 was the P31 (n,p) P32 reaction in the cyclotron, but more recently the high yield of the S32 (n,p)P32

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