• Four patients with the diagnosis of Hodgkin's disease experienced attacks of severe pain promptly after each ingestion of beer, wine, or other alcoholic drinks. Each patient experienced relief from this symptom during remissions induced by nitrogen mustard or irradiation therapy.
The explanation of this phenomenon is unknown, but it has been reported before. Anyone reporting pain after ingesting alcohol should be examined carefully for evidence of systemic disease, and patients with Hodgkin's disease should be questioned about this symptom.
Godden JO, Clagett OT, Andersen HA. SENSITIVITY TO ALCOHOL AS A SYMPTOM OF HODGKIN'S DISEASE. JAMA. 1956;160(15):1274–1277. doi:10.1001/jama.1956.02960500004002
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