This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
To the Editor:—
In a recent issue of The Journal (April 30, p. 1274) the work of the Mayo group dealing with the use of Kendall's compound E in the treatment of rheumatoid arthritis was cited and discussed. Shortly thereafter I learned of an instance in which desoxycorticosterone acetate was being used for the same purpose.In a check on four leading pharmacists, one reported "many" purchases by physicians for use in cases of rheumatoid arthritis. From our present knowledge of adrenal physiology, especially the work of Selye, the administration of desoxycorticosterone acetate in rheumatoid arthritis is to be condemned.I feel that this matter should be stressed to prevent the possible widespread, improper use of desoxycorticosterone acetate.
Gitman L. DESOXYCORTICOSTERONE ACETATE NOT A SUBSTITUTE FOR COMPOUND E IN ARTHRITIS. JAMA. 1949;140(10):909. doi:10.1001/jama.1949.02900450059021
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: