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July 23, 1949

Techniques of Histo- and Cytochemistry: A Manual of Morphological and Quantitative Micromethods for Inorganic, Organic and Enzyme Constituents in Biological Materials

JAMA. 1949;140(12):1064. doi:10.1001/jama.1949.02900470068029

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This long-awaited book on an advancing field embracing many overlapping sciences will satisfy a need felt by biochemists, physiologists and morphologists. It consists largely of selected technical procedures described in the literature dealing with both the descriptive and quantitative aspects of the subject. The greater part of the book is devoted to quantitative methods, and these are well treated, particularly those developed by the Carlsberg Laboratories in Copenhagen.

The section dealing with descriptive methods involving only localization of substances in cells and tissues could be greatly improved, both as to selection of methods and as to a discussion of principles involved. This part of the book is surpassed by the more critical but outdated book by Lison. The section dealing with deductive methods is inadequate in view of important contributions made with them. Omitted almost entirely is a consideration of methods employed in elucidating the molecular structure and organization of

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