The value of an understanding of the chemical changes that take place in the blood in disease has long been recognized. The data obtained as a result of biochemical analysis serve to supplement the information which the clinician may obtain in other ways. At present means exist for determining more completely than ever before changes in the blood that are encountered in disease. Ample application in the various branches of medicine is found, moreover, for all the knowledge obtainable concerning deviations from the normal in protein, carbohydrate, fat or inorganic metabolism as well as for aberrations of endocrine, renal or hepatic function. The literature dealing with clinical biochemistry is extremely voluminous; reports which discuss and correlate the results of investigative activity in this field are therefore welcome. In a recent review of this type, Myers and Muntwyler1 draw attention to developments of the past few years with regard to chemical changes in the blood and to the clinical significance of these changes.
CHEMICAL CHANGES IN THE BLOOD. JAMA. 1940;115(2):134–135. doi:10.1001/jama.1940.02810280046013
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