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July 27, 1940

Experimentelle Untersuchungen über die spontanen Veränderungen des Blutes in Vitro. Hinsichtlich Suspensionsstabilität, Komplementaktivität, und Antithrombinfunktion

JAMA. 1940;115(4):325-326. doi:10.1001/jama.1940.02810300065034

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Abstract

This monograph is divided into three major sections: (1) suspension stability of red blood cells, (2) complement activity and (3) antithrombin function. The introductory remarks are devoted to the earlier work of Fahræus and the author on the suspension stability of red blood cells. The main purpose of the present investigation was to study further the "stabilisierende substanz" which is adsorbed by red cells when serum or plasma is heated to body temperature and thus inhibits the aggregation tendency. This substance is considered identical with lysolecithen. Chapter 1 is devoted to the historical background of the problem. Chapter II deals with material and methods. In this section the author discusses the influence of defibrination and substances which prevent coagulation on the stabilization process, the morphologic changes of the red cells, the stabilizing process in serum and plasma, the stabilization process and splenic function, and the loss of the stabilizing process

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