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August 3, 1940


JAMA. 1940;115(5):348-354. doi:10.1001/jama.1940.02810310006003

Progressive facial hemiatrophy is a self-limited condition that always leaves in its wake a grossly apparent facial deformity. It is not a rare syndrome, and a bibliography of more than 400 articles reporting, often in detail, over 450 cases1 shows that it has not been neglected by the medical profession. No specific treatment is known that will always stop the progress of the disease. It is remarkable, then, that few observations are available in the literature on the surgical repair of the inevitable disfigurement that results. It is our purpose in this paper to summarize the present knowledge of this condition and record our experience gained in six cases from surgical reconstruction with fat, fascia and dermal grafts.

DESCRIPTION  Hemiatrophy of the face may involve any or all of the superficial tissues, affecting skin, subcutaneous fat and muscles and at times bone and cartilage as well. The disease process