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August 24, 1940

FAVISM

JAMA. 1940;115(8):632. doi:10.1001/jama.1940.02810340060025

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Abstract

To the Editor:—  I am contriving some research work on a blood disease, "favism," on which many studies were made by my co-workers and myself in 1936. At that time I was professor of medicine at the University of Sassari, Italy, and I had an opportunity to observe many cases of this disease, as it is quite common on the Italian island of Sardinia. The interest in this disease is due not only to the suddenness of the attacks, to the resulting anemia and to the high death rate but also to the fact that complete clarification of its pathogenesis may cast light on the mechanism of hemolysis in general and of hemoglobinurias in particular.Despite the fact that two cases were reported in volumes 101 and 109 of The Journal by McCrae and Ullery and by Hutton, the disease is not well known in the United States. It is

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