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This brief monograph is a preliminary report of a study of the metabolism of vitamin B1 during pregnancy and the puerperium. About two thirds of the report is devoted to a discussion of methods. With the method of Ritsert, which was adopted, there was observed a loss of vitamin B1 up to 25 per cent in blood, and this must be allowed for in calculating results. The amount of vitamin B1 in the serum is from 3 to 4 micrograms per hundred centimeters of blood. The vitamin B1 content in the serum is slightly higher in pregnant women than in normal persons. The normal urinary excretion of vitamin B1 amounts to from 100 to 200 micrograms daily. The author believes that if the excretion in the urine is below 100 micrograms it indicates a deficiency of vitamin B1. Pregnant women eliminate about 170 micrograms
Zwanglose Abhandlungen auf dem Gebiete der Frauenheilkunde. JAMA. 1940;115(8):639. doi:10.1001/jama.1940.02810340067039
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