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September 7, 1940

Vitamin D: Chemistry, Physiology, Pharmacology, Pathology, Experimental and Clinical Investigations

JAMA. 1940;115(10):881-882. doi:10.1001/jama.1940.02810360069033

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The authors of this book are among the chief proponents of the use of massive doses of vitamin D in the treatment of arthritis, "pollinosis" and a variety of clinical conditions other than rickets. Therefore it is not surprising to find that this is not the conventional review of vitamin D which its title suggests but, on the contrary, is essentially a defense of the empirical use of vitamin D as a pharmacologic agent. The earlier chapters of the book are devoted to a brief review of the chemistry of vitamin D, the relative potency of various forms of the vitamin (including the several forms of vitamin D milk), a description of biologic and chemical methods for determining vitamin D, and a discussion of the physiologic effects of the vitamin, including its possible mode of action in the prevention or healing of rickets. Throughout the review much space is given

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