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September 7, 1940

Biokhimiya adrenalina

JAMA. 1940;115(10):882. doi:10.1001/jama.1940.02810360070036

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Problems pertaining to the biochemistry of epinephrine did not receive the exhaustive treatment in literature accorded the physiology and the pharmacology of epinephrine. The author points out that, as a hormone and a substance genetically and functionally related to the mediators of the sympathetic nervous system, epinephrine presents a most important and fascinating subject for biochemical investigation. In attempting to present a systematic treatment of the fundamental problems of the biochemistry of epinephrine the author utilizes the accepted theories and hypotheses as well as his own ideas based on the investigations carried out in his laboratory. The volume contains eight chapters dealing with the chemistry, the role of secretion, the various forms in which epinephrine exists in the living organism, epinephrine as a mediator of sympathetic nervous impulses, the chemical nature of sympathenes, the formation of epinephrine, the oxidation products of epinephrine and the role of epinephrine in metabolism and

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