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October 5, 1940

Cyclopropane Anesthesia

JAMA. 1940;115(14):1223. doi:10.1001/jama.1940.02810400075037

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This book represents a review of the literature on cyclopropane as an anesthetic agent. The physiologic and chemical properties of cyclopropane are presented, as are also the concentrations required for anesthesia based on accurate determinations of the amount of cyclopropane in the patient's blood. The author's results are compared to the results of others. The effect of cyclopropane on the various systems of the body is considered— the circulatory system, with special emphasis on the effect of the agent on the heart, and the effect on the respiratory system, gastrointestinal tract, blood and tissues. The section on the clinical administration of cyclopropane is brief and not as complete as a clinician would wish it to be. Complications are dealt with briefly, as are indications and contraindications. The explosive hazards of cyclopropane are considered briefly. Although common precautions which should be taken when this agent is employed are mentioned, many of

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