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February 10, 1951


JAMA. 1951;145(6):407. doi:10.1001/jama.1951.02920240043013

With the advance of medical diagnosis and therapy the importance of the chemical laboratory has increased; the number and diversity of the analyses carried out per day by the laboratory has also become much greater. To obtain uniformly reliable data from a busy chemical laboratory requires constant supervision by either the director of the laboratory or an equally qualified person. Normally such personnel does not have sufficient time to devote to detailed supervision of the many methods employed. As one solution to this problem a large clinical laboratory has recently borrowed from industry a procedure known as quality control. This procedure, widely used to detect, with a minimum of inspection, any undue variations in a manufacturing process, has been successfully adapted to the clinical laboratory. Here it provides a simple and continuous check on the accuracy of the various chemical technics employed. The method consists of the setting up of