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March 3, 1951

REACTIONS TO DEXTROSE

JAMA. 1951;145(9):666. doi:10.1001/jama.1951.02920270060025

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Abstract

To the Editor:—  In an editorial entitled "Reactions to Dextrose," in The Journal of Dec. 16, 1950, attention is called to the claim by Randolph and his co-workers that allergic reactions from intravenous injection of dextrose occur in corn-sensitive patients. The editorial appears to support the validity of this claim by several statements, among them: "These authors demonstrated that crystalline sugars prepared from corn starch may cause intensive allergic reactions when ingested by persons highly sensitive to corn." It is stated further: "It is therefore not surprising that there should be occasional reactions to intravenous injections of dextrose that is prepared from simple hydrolysis of corn starch."We believe that the failure to present a more complete version of the picture of certain phases of food allergy in the editorial may be misleading and productive of unnecessary fears. We are aware that a small group of allergists for some time

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