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March 3, 1951

REACTIONS TO DEXTROSE

Author Affiliations

Associate Professor of Clinical Medicine, Cornell University Medical College, New York.

JAMA. 1951;145(9):666. doi:10.1001/jama.1951.02920270060026

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Abstract

To the Editor:—  With reference to the editorial "Reactions to Dextrose" (J. A. M. A.144:1379 [Dec. 16] 1950), there can be no doubt that the implications of Randolph's claim for the allergenicity of dextrose by infusion are too serious to be disregarded. The possible danger to the public from this source is particularly pertinent in view of threatened atomic warfare, since dextrose might have to be used intravenously on a broad scale. Dr. Randolph's conclusions are entirely logical, but, like the superstructure of Lysenko's genetics, the underlying premise lacks scientific validity. Randolph holds that allergy for cereals is common, that corn is the first offender among food allergens and that its derivatives, sugar, syrup and oil, are allergenic excitants. These claims were given so much publicity that the United States Food and Drug Administration made a thorough exploration of the facts and theories about two years ago, in

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