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March 10, 1951

Penicillin: Its Practical Application

JAMA. 1951;145(10):770. doi:10.1001/jama.1951.02920280082032

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It is completely fitting and proper that the man who discovered penicillin should edit the second edition of a book about this drug. The first edition of the book was published in 1946. Knowledge of the usefulness and limitations of penicillin has increased greatly since that time, and Fleming has endeavored to portray the present day status of the drug in this edition. The authors of the various chapters have rewritten their sections, but some did not appear to carry out a sufficiently critical review or to take into full account all the published literature as they should have done. This is apparent when one notes the meager bibliography following certain chapters. The topical use of penicillin preparations is given undue prominence, and the hazards of such use are not given sufficient consideration. Some reduplication of observations concerning the use of penicillin occur, but this is not at all unusual

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