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April 28, 1951


Author Affiliations

Chicago; McHenry, Ill.

From the Department of Nervous and Mental Diseases, Northwestern University Medical School; The Division of Neurology and Psychiatry of Wesley Memorial Hospital, Chicago, Woodstock Public Hospital. Woodstock, Ill.

JAMA. 1951;145(17):1342. doi:10.1001/jama.1951.72920350001008

The following clinical note presents the case of a worker exposed to dichlorodiphenyltrichloroethane (DDT) who had a four year illness characterized by neurological disturbances and mild leukopenia. A causal relationship between illness and exposure to DDT is suggested by the fact that the patient improved when taken off his regular job.

REPORT OF CASE  B. S., a 24 year old man, was seen first on May 20, 1950, complaining of weakness of four years duration, poor appetite and restless sleeping. His condition occurred in paroxysms until May 16, when he observed a distinct increase in weakness and an indistinction in his speech, so that he was not understood by his associates. He remained home for two days and then returned to work on May 19. On June 2 his fatigue became marked and severe. When first examined by one of us (L. G.) he complained of the following: severe fatigue,