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May 26, 1951

Toxæmias of Pregnancy: Human and Veterinary.

JAMA. 1951;146(4):414. doi:10.1001/jama.1951.03670040114051

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This monograph presents material read before a meeting of European and North American authorities. There are short presentations on the physiology of pregnancy, the pathologic lesions and changes occurring during various toxemias, and certain theories of etiology.

One of the most interesting etiological theories is the theory of Schneider. He postulates that certain thromboembolic phenomena and pathologic changes found in experimental animals after injection of thromboplastin resemble changes occurring in certain complications of pregnancy, including toxemia. Schneider stresses several possible portals of entry for thromboplastin into the maternal circulation from the conceptus. He suggests that the frequently seen, isolated, retroplacental hemorrhages may play a major role in the mobilization of thromboplastin into the maternal circulation in human toxemia.

Despite the variability inherent in a presentation by many authors, this book is a valuable monograph replete with excellent sources of bibliography.

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