Since aerosol inhalation therapy was advocated by Barach, Segal, Abramson and others1 for the treatment of pulmonary edema, bronchial asthma, chronic bronchitis and certain suppurative lung conditions, penicillin by aerosol inhalation, in addition to its parenteral injection, has been employed when antibiotics are indicated. Bronchial dilators and sympathomimetic amines also now are given by aerosol. Because the duration of aerosol treatment is long, and the treatment may be prescribed for weeks or months, the practical problem arises as to how such therapy can be carried out at home.
Efforts to provide a continuous stream of air pressure were made first by supplying a nebulizer with a rubber tube, which, in turn, was attached to a bicycle pump. This required another person to pump the nebulizer while the patient inhaled the medication. In the next attempt the inner tube from a bus or truck tire was inflated, and when it
Sheldon JM, Lovell RG, Mathews KP. AEROSOL THERAPY: VACUUM CLEANER AS A PRACTICAL SOURCE OF POSITIVE PRESSURE FOR NEBULIZATION. JAMA. 1951;146(7):648–650. doi:10.1001/jama.1951.63670070008009e
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