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July 14, 1951


Author Affiliations

Manchester University, Manchester 13, England.

Middlesex Hospital, London, W. 1.

JAMA. 1951;146(11):1063. doi:10.1001/jama.1951.03670110083032

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To the Editor:  —In The Journal of March 31 (145:978) there is a clinical note on successful treatment of mismatched blood transfusion by alkalinization with sodium bicarbonate. The authors consider that this treatment is not generally known, but surely it should be known by now, as it was used for blackwater fever (where there is similar hematin blockage of renal tubules) some 30 years ago. We stressed its value in mismatched blood transfusion in a paper written in 1925 (Brit. J. Exp. Path. 6:247).

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