The distinct increase in definitive surgical operations for intrathoracic diseases and lesions during the past two decades has caused an even greater increase in the incidence of diagnostic procedures to confirm or to help rule out the presence of pathologic processes within the chest. As the mortality and morbidity following thoracic surgical procedures have decreased and inversely the cures and good results have increased, it has been extremely important and of universal interest that untoward reactions, morbidity, or mortality attendant on diagnostic procedures be reduced to an absolute minimum.
One of the most distressing and sometimes fatal1 complications of endoscopic procedures has been the so-called "anesthetic reaction." In discussions with our colleagues, it has been evident that there has been a decided difference in opinion regarding the incidence and severity of the anesthetic reactions, as well as the anesthetic agent of choice. The opinions voiced have varied from the
Weisel W, Tella RA. REACTION TO TETRACAINE (PONTOCAINE®) USED AS TOPICAL ANESTHETIC IN BRONCHOSCOPY: STUDY OF 1,000 CASES. JAMA. 1951;147(3):218–222. doi:10.1001/jama.1951.03670200010003
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