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October 6, 1951

CORTISONE IN THE TREATMENT OF OSTEOARTHRITIS OF THE HIPS

Author Affiliations

Philadelphia

From the Arthritis Section, Department of Medicine, Hospital of the University of Pennsylvania.

JAMA. 1951;147(6):551-553. doi:10.1001/jama.1951.03670230017005
Abstract

Although the literature on cortisone in the therapy of various diseases has become voluminous, little has been said concerning its use in degenerative joint disease (osteoarthritis). This is particularly true with regard to degenerative joint disease of the hips, so-called malum coxae senilis. There have been several encouraging reports on the efficacy of corticotrophin (ACTH) or cortisone in other forms of degenerative joint disease.

Hench and others1 reported a patient with degenerative joint disease of the left knee, who received cortisone for the treatment of leukemia cutis. The pain and stiffness in the knee was ameliorated and remained improved when the patient last was seen, a month later. Thorn and others2 described marked alleviation of symptoms in a patient who had generalized degenerative joint disease with involvement of both hips. Therapy in this case consisted of 40 mg. of corticotrophin daily in divided doses for seven days. Dale

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