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October 6, 1951


JAMA. 1951;147(6):593. doi:10.1001/jama.1951.03670230059020

Comparison of Amithiozone and Paraaminosalicylic Acid.  —The introduction by Domagk of amithiozone (conteben®) as a remedy for tuberculosis has been followed by a spate of publications on this subject, particularly in Germany, where this preparation is widely used. It has been well received in Sweden, where its chief competitor in this field is paraaminosalicylic acid. In 1948 the Swedish National Association Against Tuberculosis sponsored a statistical investigation of the comparative merits of paraaminosalicylic acid and expectant treatment of tuberculosis, in which results with paraaminosalicylic acid were most favorable. During the latter half of 1949 and early in 1950, an attempt was made at the Söderby Hospital to ascertain which of the two remedies, amithiozone or paraaminosalicylic acid, is the more effective in pulmonary tuberculosis.This investigation has been reported on by Dr. Rune Raxell in the journal of the Swedish Medical Association, Svenska Läkartidningen, for Aug. 3, 1951. Fifty-four

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