Reports of human infections with Leptospira canicola are rare, especially in the literature of the United States. In 1946 Rosenbaum1 reported the sixth case in the United States. More recently, Minkenhof2 compiled from the world's literature a total of 98 cases, of which seven were from this country. Molner and others3 described the disproportionately low incidence of leptospiral infections of all types in the United States as compared with other nations and attributed this fact to the failure either to recognize these diseases or to report diagnosed cases. In a consideration of canicola fever, these assumptions appear to be well grounded in view of the prevalence of the infection in the canine population of many areas of the United States.4
Leptospirosis due to Lept. canicola has been considered a relatively benign disease in the human, but fatal cases have been reported.5 Its onset may be
Stagg JF, Leibovitz A. AUREOMYCIN AND PENICILLIN THERAPY IN CANICOLA FEVER: REPORT OF A CASE. JAMA. 1951;147(11):1048–1051. doi:10.1001/jama.1951.73670280013012f
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