The term "diuresis" is derived from the Greek διά, meaning "through" and ο[unk]ρε[unk]ν, to urinate, and implies not only an increased excretion of urinary water, but also an increase in other urinary constituents. While some diuretic agents actually promote the excretion of urine, others, especially the more useful ones, act primarily on one constituent of urine, increasing the others only secondarily and not always regularly. Therefore, the principal actions of the various diuretic agents must be considered in relation to special therapeutic problems.
At the present, diuretics are used mainly to remove via the kidneys excess fluid and electrolytes that have been retained in the body, although diuretics may also be employed for irrigating the urinary passages with water, for promoting dehydration, or for establishing a normal urinary output in oliguric states. Therefore, their principal use is in edema. Since edema fluid is composed mainly of water and electrolytes, especially
Schroeder HA. USE OF DIURETIC AGENTS. JAMA. 1951;147(12):1109–1118. doi:10.1001/jama.1951.03670290017006
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: