In 1949, we studied the literature on cholecystitis in childhood.1 This included a critical review of most cases described, as well as a survey by letter of 21 major clinics in America and England. We found that many cases of hepatitis and peritonitis had been inaccurately reported as cholecystitis. We judged that there were less than 400 authentic cases of cholecystitis since the first report in 1722.2 Although only 19 had common duct stone, we learned that cholecystitis in childhood is often complicated by jaundice, apparently obstructive. The significance of this observation lies in the increased incidence of hepatocellular types of jaundice. However, its clinical importance is tempered by the rare occurrence of cholecystitis in young persons.
Our review included two fatal cases of cholecystitis with common duct obstruction, proved at autopsy. The patients' condition had been misdiagnosed as infectious hepatitis. We encountered the same diagnostic problem in
Ulin AW, Nosal JL, Martin WL. CHOLECYSTITIS IN CHILDHOOD: REPORT OF A CASE WITH COMMON DUCT CALCULI. JAMA. 1951;147(15):1443–1444. doi:10.1001/jama.1951.73670320007013c
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