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December 8, 1951

The Odyssey of Modern Drug Research: Pharmaceutical Manufacture; its Science and Economics

JAMA. 1951;147(15):1506. doi:10.1001/jama.1951.03670320106041

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The story of the development of modern therapeutic agents is too often inadequately appreciated. Vaguely, we know that someone discovers them, others study their action and determine their usefulness, and still others make them available for prescription use. This book presents, in sufficient detail, the story of the discovery and development of some of these agents. No one can follow it without gaining a greater respect for this triad of workers, whose combined efforts have resulted in our modern chemotherapeutic drugs.

The author has chosen certain illustrative examples of such agents, and their detailed story affords entertaining and informative reading. He offers the facts behind the discovery and development of the antibiotics, the sulfonamides, and the adrenocortical steroids and also presents the essential part that modern pharmaceutical companies have played in making them available. Also presented is an altogether engaging glance behind the scenes in a discussion of anticipated developments

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