[Skip to Content]
[Skip to Content Landing]
May 17, 1952


Author Affiliations

600 S. Kingshighway St. Louis

JAMA. 1952;149(3):297. doi:10.1001/jama.1952.02930200083023

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  Recent announcements in the press of a method to control hypertension by the use of hexamethonium chloride and hydrazinophthalazine have inspired considerable confusion and conflicting comments in both lay and medical circles. Some tabloid newspapers gave a distorted, overenthusiastic view, other papers were reasonably factual, but several reprinted follow-up stories inspired by another investigator branding the method as "dangerous." In addition, literature mailed to physicians by the manufacturer of a preparation of hexamethonium chloride contained erroneous statements attributed to me. Since the truth lies between these conflicting statements, I am attempting to clarify the confusion.A method for the partial temporary control of arterial hypertension has been developed, a preliminary report of which was published in the A. M. A. Archives of Internal Medicine (89:523 [April] 1952). This method has been extended to include approximately 120 patients suffering from arterial hypertension of all degrees of severity,

First Page Preview View Large
First page PDF preview
First page PDF preview