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Article
May 24, 1952

WOLFF-PARKINSON-WHITE SYNDROME IN AN INFANT

JAMA. 1952;149(4):363-364. doi:10.1001/jama.1952.72930210001013
Abstract

The syndrome characterized by paroxysms of auricular tachycardia, fibrillation, or flutter in association with the electrocardiographic picture of a short P-R interval and a prolonged QRS interval as seen in healthy adults was described in 1930 by Wolff, Parkinson, and White.1 The electrocardiographic findings had been noted first by Wilson2 in 1915, who produced the characteristic abnormalities by varying types of vagal stimulation. Subsequently, many publications have described single or multiple examples of this interesting condition, but it was not until 1946 that the typical features of the syndrome were noted in an infant, aged 14 weeks.3 In all, four infants have been reported as having the Wolff-Parkinson-White syndrome, aged 5 weeks,4 14 weeks (two cases),5 and 4 1/2 months.6 In the infant on whom we are reporting paroxysmal tachycardia first developed at the age of 5 weeks, and the true nature of the

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