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June 28, 1952


Author Affiliations

From the Sarah Morris Hospital for Children and the Department of Bacteriology and Virology, Michael Reese Hospital.

JAMA. 1952;149(9):829-832. doi:10.1001/jama.1952.72930260004009b

During the past decade there has been an increasing interest manifested in systemic fungus disease as evidenced by the large number of reports in the literature. Actinomycosis, blastomycosis, coccidioidomycosis, histoplasmosis, torulosis, moniliasis, sporotrichosis, and aspergillosis represent a group of mycotic diseases that occur in the United States and that may become disseminated, often terminating fatally.1 However, endocarditis due to fungi is exceedingly rare2 and, to the best of our knowledge, has not been described in infancy and has been reported only once in a child under 15 years of age.3

Twenty-four cases of mycotic endocarditis have been found in the literature.4 Among these, the organism was identified in 19 instances. In four cases an unidentified fungus was present, and in one case a fungus was identified in a blood culture but no autopsy was performed. In nine of the 24 cases, the disease was caused by