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June 28, 1952


Author Affiliations

Oak Park, Ill.

JAMA. 1952;149(9):832-833. doi:10.1001/jama.1952.72930260007009c

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Corticotropin (ACTH) and cortisone are known to affect thyroid function. Forsham reported experiments demonstrating a slowed iodine uptake in normal people taking cortisone or corticotropin. The decreased thyroid function may not be reflected in an increase of cholesterol in the blood, according to Conn. Hypothyroidism in patients receiving corticotropin or cortisone may also not be demonstrable by the usual method of measuring basal metabolism because of the known calorigenic effect of corticotropin and cortisone. Of the many complications of corticoid therapy, thyroiditis has not been reported to date.

REPORT OF A CASE  J. R. was first seen in December, 1949. He had been disabled by severe rheumatoid arthritis for months. All the joints in his extremities were painful, tender, and swollen. Large subcutaneous nodules were present below the elbows. While he was under observation in West Suburban Hospital, coronary thrombosis developed. Six weeks after the coronary episode he consulted another

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