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June 13, 1953


Author Affiliations

44 W. 55th St., New York 19.

JAMA. 1953;152(7):628. doi:10.1001/jama.1953.03690070062024

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To the Editor:  —With respect to the clinical note in The Journal, April 18 (page 1403), it is not unusual, in patients with cardiovascular disease, to find both anemia and optic neuritis associated with subacute bacterial endocarditis. For example, Friedberg states: "Optic neuritis and even choked disk have been described as toxic manifestations of the disease" (that is: bacterial endocarditis) (Diseases of the Heart, Philadelphia, W. B. Saunders Company, 1949, p. 791). Kauntze has published a report of seven cases of subacute bacterial endocarditis in which optic neuritis occurred (Brit. Heart J.9:34, 1947). Statements in "Genetics in Ophthalmology" by Sorsby and "Clinical Neuro-Ophthalmology" by Walsh confirm this fact, described first in the classic paper by Falconer entitled "The Importance of Optic Neuritis and Retinal Hemorrhages in the Diagnosis of Chronic Septic Endocarditis" (Quart. J. Med.3:107, 1910).The omission of reference to these facts from the clinical

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