A type of urinary sediment believed to be characteristic of periarteritis nodosa and lupus erythematosus disseminatus was described by Krupp1 in 1943. Only one report, that of Miale,2 has appeared in the literature to confirm this observation. It is well recognized, of course, that hematuria is frequently present in periarteritis nodosa.
Krupp reported the presence in a single urine specimen of red blood cells, red cell casts, oval fat bodies, fatty and waxy casts, and, frequently, broad casts. There was also an abnormal amount of protein present. These findings were demonstrated in 14 of 21 cases of periarteritis nodosa and lupus erythematosus studied. The changes in the urinary sediment were found to vary with the state of the patient, being more extreme during clinical exacerbation and tending to disappear during remission. According to Krupp, red cell casts are the result of glomerulitis, and in acute glomerulonephritis they are
Cole LR. PERIARTERITIS NODOSA: REPORT OF CASE WITH CHARACTERISTIC URINARY SEDIMENT. JAMA. 1952;149(18):1649–1650. doi:10.1001/jama.1952.72930350005009d
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