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September 6, 1952

L'hypertension artérielle permanente et sa thérapeutique: Indications médicales des interventions neuro-endocriniennes

JAMA. 1952;150(1):62. doi:10.1001/jama.1952.03680010068032

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This monograph gives a competent summary of present knowledge of the diagnosis, pathogenesis, course, and treatment of essential and malignant hypertension. After a brief historical review the author describes the vascular, endocrine, parenchymatous, and other lesions of essential hypertension, malignant hypertension, and experimental hypertension. In the next chapter he describes the symptoms and signs of the four classic stages of essential hypertension, namely, simple hypertension (stage 1), hypertension with arteriolosclerosis (stage 2), hypertension with severe arteriolosclerosis and complications (stage 3), and malignant hypertension (stage 4). Then follows a chapter dealing with prognosis, methods of clinical and laboratory examination to determine the severity of the hypertensive process, and the pathophysiology and pathogenesis of essential and malignant hypertension. The second part of the monograph discusses treatment. The first chapter describes practically all of the medical therapy currently in vogue or recently proposed and the various forms of surgical intervention, including extensive but

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