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May 5, 1956


JAMA. 1956;161(1):66-67. doi:10.1001/jama.1956.02970010068018

Kcloids are admittedly a frustrating problem for both surgeon and dermatologist. The true keloid is a fibroma usually of the fibrous tissue of the corium. The false keloid, or hypertrophic scar, cannot be differentiated histologically from the true keloid but is commoner and occurs following some form of trauma. Being inflammatory in nature, it often improves spontaneously. The commonest sites of true keloids are the chest, neck, and ears. The tendency to keloid formation is not constant throughout life but may come and go.1 Keloids are most commonly seen in patients between the ages of 10 and 19, and new formations are uncommon after the menopause. Why in normal wound healing fibroblasts do not continue to proliferate beyond the optimal point is not known, but when they do a hypertrophic scar is produced. It is known that normal wound healing is favored by careful apposition of tissues, good general