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The second volume of this series is similar in purpose and make-up to the first, which appeared in 1951. The purpose is to provide a comprehensive summary of data on compounds having biological properties and thus to aid in the correlation of structure with activity. Each chapter, written by an authority, includes compounds having specific biological activity. Where it is not feasible, because a category may be too large to include all the information in a single chapter, a subdivision is made on a chemical basis. The present volume contains four chapters dealing with cardiac glycosides, synthetic estrogens, arylpiperidine analgesics, and β-haloethylamine adrenergic blocking agents. Most of the chapters contain a large portion of the material in table form in order to conveniently correlate activity and structure. Each chapter contains numerous references to the original literature.
Medicinal Chemistry. Volume II. JAMA. 1956;162(3):258. doi:10.1001/jama.1956.02970200106026
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