During the past 15 years there has been a marked decrease in the number of patients who have required surgical procedures for treatment of inflammatory disease of the temporal bone. This decrease is the result of the profound influence that treatment with the sulfonamide and antibiotic drugs has exerted on acute inflammation of the middle ear and mastoid. The result of decrease in the incidence and destructive effect of acute infection is seen in lessening of the incidence of chronic inflammation in these regions. There remains, however, a considerable reservoir of patients who suffer from the effects of chronic suppuration of the ear that had its inception in the preantibiotic era. In addition, there are patients who currently undergo chronic inflammation of the ear as a result either of infection by resistant strains of micro-organisms or of inadequate treatment of acute infections.
The predominant factors in the production of chronic
Simonton KM. SELECTION OF PATIENTS FOR SURGICAL PROCEDURES IN CHRONIC SUPPURATIVE OTITIS MEDIA. JAMA. 1952;150(5):461–464. doi:10.1001/jama.1952.03680050027007