This book will undoubtedly be widely read. Unfortunately paralysis agitans is a widespread and disabling condition. As there has been no truly satisfactory treatment for this chronic disease, many of its victims will look hopefully to the possibility of relief that is held out here. One of the barriers to investigating this condition lies in the fact that the disease has never been produced in animals and cannot, therefore, be studied by investigations in laboratory animals. Observations regarding the condition, its cause, pathological physiology, and treatment, must be made on man himself. It is notoriously difficult or impossible to conduct human investigations with the same scientific care that can be exerted with the laboratory animal. This is all the more reason why observations on human beings should be even more painstakingly made than those in the experimental laboratory. Unfortunately this book and the material recorded here do not meet that
The Neurosurgical Alleviation of Parkinsonism. JAMA. 1956;162(13):1266. doi:10.1001/jama.1956.02970300066027
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